8CY8
apo form Cryo-EM structure of Campylobacter jejune ketol-acid reductoisommerase crosslinked by Glutaraldehyde
Summary for 8CY8
Entry DOI | 10.2210/pdb8cy8/pdb |
EMDB information | 27070 |
Descriptor | Ketol-acid reductoisomerase (NADP(+)), PENTANEDIAL (2 entities in total) |
Functional Keywords | ketol-acid reductoisomerase, isomerase, enzyme stability, dodecamer, branched-chain amino acid |
Biological source | Campylobacter jejuni |
Total number of polymer chains | 12 |
Total formula weight | 429192.83 |
Authors | Zheng, S.,Guddat, L.W. (deposition date: 2022-05-23, release date: 2023-02-01, Last modification date: 2024-06-12) |
Primary citation | Lv, Y.,Zheng, S.,Goldenzweig, A.,Liu, F.,Gao, Y.,Yang, X.,Kandale, A.,McGeary, R.P.,Williams, S.,Kobe, B.,Schembri, M.A.,Landsberg, M.J.,Wu, B.,Bruck, T.B.,Sieber, V.,Boden, M.,Rao, Z.,Fleishman, S.J.,Schenk, G.,Guddat, L.W. Enhancing the Thermal and Kinetic Stability of Ketol-Acid Reductoisomerase, a Central Catalyst of a Cell-Free Enzyme Cascade for the Manufacture of Platform Chemicals Appl Biosci, 2022 Cited by DOI: 10.3390/applbiosci1020011PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.94 Å) |
Structure validation
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