8CY8

apo form Cryo-EM structure of Campylobacter jejune ketol-acid reductoisommerase crosslinked by Glutaraldehyde

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0004455	molecular_function	ketol-acid reductoisomerase activity
A	0005829	cellular_component	cytosol
A	0009082	biological_process	branched-chain amino acid biosynthetic process
A	0009099	biological_process	L-valine biosynthetic process
A	0016491	molecular_function	oxidoreductase activity
A	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
A	0050661	molecular_function	NADP binding
A	1901705	biological_process	L-isoleucine biosynthetic process
B	0000287	molecular_function	magnesium ion binding
B	0004455	molecular_function	ketol-acid reductoisomerase activity
B	0005829	cellular_component	cytosol
B	0009082	biological_process	branched-chain amino acid biosynthetic process
B	0009099	biological_process	L-valine biosynthetic process
B	0016491	molecular_function	oxidoreductase activity
B	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
B	0050661	molecular_function	NADP binding
B	1901705	biological_process	L-isoleucine biosynthetic process
C	0000287	molecular_function	magnesium ion binding
C	0004455	molecular_function	ketol-acid reductoisomerase activity
C	0005829	cellular_component	cytosol
C	0009082	biological_process	branched-chain amino acid biosynthetic process
C	0009099	biological_process	L-valine biosynthetic process
C	0016491	molecular_function	oxidoreductase activity
C	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
C	0050661	molecular_function	NADP binding
C	1901705	biological_process	L-isoleucine biosynthetic process
D	0000287	molecular_function	magnesium ion binding
D	0004455	molecular_function	ketol-acid reductoisomerase activity
D	0005829	cellular_component	cytosol
D	0009082	biological_process	branched-chain amino acid biosynthetic process
D	0009099	biological_process	L-valine biosynthetic process
D	0016491	molecular_function	oxidoreductase activity
D	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
D	0050661	molecular_function	NADP binding
D	1901705	biological_process	L-isoleucine biosynthetic process
E	0000287	molecular_function	magnesium ion binding
E	0004455	molecular_function	ketol-acid reductoisomerase activity
E	0005829	cellular_component	cytosol
E	0009082	biological_process	branched-chain amino acid biosynthetic process
E	0009099	biological_process	L-valine biosynthetic process
E	0016491	molecular_function	oxidoreductase activity
E	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
E	0050661	molecular_function	NADP binding
E	1901705	biological_process	L-isoleucine biosynthetic process
F	0000287	molecular_function	magnesium ion binding
F	0004455	molecular_function	ketol-acid reductoisomerase activity
F	0005829	cellular_component	cytosol
F	0009082	biological_process	branched-chain amino acid biosynthetic process
F	0009099	biological_process	L-valine biosynthetic process
F	0016491	molecular_function	oxidoreductase activity
F	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
F	0050661	molecular_function	NADP binding
F	1901705	biological_process	L-isoleucine biosynthetic process
G	0000287	molecular_function	magnesium ion binding
G	0004455	molecular_function	ketol-acid reductoisomerase activity
G	0005829	cellular_component	cytosol
G	0009082	biological_process	branched-chain amino acid biosynthetic process
G	0009099	biological_process	L-valine biosynthetic process
G	0016491	molecular_function	oxidoreductase activity
G	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
G	0050661	molecular_function	NADP binding
G	1901705	biological_process	L-isoleucine biosynthetic process
H	0000287	molecular_function	magnesium ion binding
H	0004455	molecular_function	ketol-acid reductoisomerase activity
H	0005829	cellular_component	cytosol
H	0009082	biological_process	branched-chain amino acid biosynthetic process
H	0009099	biological_process	L-valine biosynthetic process
H	0016491	molecular_function	oxidoreductase activity
H	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
H	0050661	molecular_function	NADP binding
H	1901705	biological_process	L-isoleucine biosynthetic process
I	0000287	molecular_function	magnesium ion binding
I	0004455	molecular_function	ketol-acid reductoisomerase activity
I	0005829	cellular_component	cytosol
I	0009082	biological_process	branched-chain amino acid biosynthetic process
I	0009099	biological_process	L-valine biosynthetic process
I	0016491	molecular_function	oxidoreductase activity
I	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
I	0050661	molecular_function	NADP binding
I	1901705	biological_process	L-isoleucine biosynthetic process
J	0000287	molecular_function	magnesium ion binding
J	0004455	molecular_function	ketol-acid reductoisomerase activity
J	0005829	cellular_component	cytosol
J	0009082	biological_process	branched-chain amino acid biosynthetic process
J	0009099	biological_process	L-valine biosynthetic process
J	0016491	molecular_function	oxidoreductase activity
J	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
J	0050661	molecular_function	NADP binding
J	1901705	biological_process	L-isoleucine biosynthetic process
K	0000287	molecular_function	magnesium ion binding
K	0004455	molecular_function	ketol-acid reductoisomerase activity
K	0005829	cellular_component	cytosol
K	0009082	biological_process	branched-chain amino acid biosynthetic process
K	0009099	biological_process	L-valine biosynthetic process
K	0016491	molecular_function	oxidoreductase activity
K	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
K	0050661	molecular_function	NADP binding
K	1901705	biological_process	L-isoleucine biosynthetic process
L	0000287	molecular_function	magnesium ion binding
L	0004455	molecular_function	ketol-acid reductoisomerase activity
L	0005829	cellular_component	cytosol
L	0009082	biological_process	branched-chain amino acid biosynthetic process
L	0009099	biological_process	L-valine biosynthetic process
L	0016491	molecular_function	oxidoreductase activity
L	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
L	0050661	molecular_function	NADP binding
L	1901705	biological_process	L-isoleucine biosynthetic process

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1740
Details	Domain: {"description":"KARI C-terminal knotted","evidences":[{"source":"PROSITE-ProRule","id":"PRU01198","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	12
Details	Active site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00435","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	156
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00435","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---