8CX3

Crystal structure of full-length mesothelin

8CX3 の概要

• エントリーDOI: 10.2210/pdb8cx3/pdb
• 分子名称: Isoform 4 of Mesothelin, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• 機能のキーワード: mesothelin, cell adhesion
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 214873.41

構造登録者

Zhan, J.,Esser, L.,Xia, D. (登録日: 2022-05-19, 公開日: 2023-02-01, 最終更新日: 2023-10-25)

• 主引用文献: Zhan, J.,Lin, D.,Watson, N.,Esser, L.,Tang, W.K.,Zhang, A.,Liu, X.,Hassan, R.,Gleinich, A.,Shajahan, A.,Azadi, P.,Pastan, I.,Xia, D.; Structures of Cancer Antigen Mesothelin and Its Complexes with Therapeutic Antibodies.; Cancer Res Commun, 3:175-191, 2023; PubMed: 36968141; DOI: 10.1158/2767-9764.CRC-22-0306

実験手法

X-RAY DIFFRACTION (3.609 Å)