8CUH
Crystal structure of human TEAD2 complexed with its inhibitor TM2.
Summary for 8CUH
Entry DOI | 10.2210/pdb8cuh/pdb |
Descriptor | Transcriptional enhancer factor TEF-4, 4-[3-(2-cyclohexylethoxy)benzoyl]-N-phenylpiperazine-1-carboxamide (3 entities in total) |
Functional Keywords | transcription factor, transcription-transcription inhibitor complex, transcription |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 55849.31 |
Authors | |
Primary citation | Hu, L.,Sun, Y.,Liu, S.,Erb, H.,Singh, A.,Mao, J.,Luo, X.,Wu, X. Discovery of a new class of reversible TEA-domain transcription factor inhibitors with a novel binding mode. Elife, 11:-, 2022 Cited by PubMed: 36398861DOI: 10.7554/eLife.80210 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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