8CRB

Cryo-EM structure of PcrV/Fab(11-E5)

Summary for 8CRB

Entry DOI	10.2210/pdb8crb/pdb
EMDB information	16807
Descriptor	Heavy chain, Light chain, Maltose/maltodextrin-binding periplasmic protein,Type III secretion protein PcrV (3 entities in total)
Functional Keywords	antibody t3ss tip protein, antimicrobial protein
Biological source	Pseudomonas aeruginosa More
Total number of polymer chains	3
Total formula weight	122539.15
Authors	Yuan, B.,Simonis, A.,Marlovits, T.C. (deposition date: 2023-03-08, release date: 2023-11-22)
Primary citation	Simonis, A.,Kreer, C.,Albus, A.,Rox, K.,Yuan, B.,Holzmann, D.,Wilms, J.A.,Zuber, S.,Kottege, L.,Winter, S.,Meyer, M.,Schmitt, K.,Gruell, H.,Theobald, S.J.,Hellmann, A.M.,Meyer, C.,Ercanoglu, M.S.,Cramer, N.,Munder, A.,Hallek, M.,Fatkenheuer, G.,Koch, M.,Seifert, H.,Rietschel, E.,Marlovits, T.C.,van Koningsbruggen-Rietschel, S.,Klein, F.,Rybniker, J. Discovery of highly neutralizing human antibodies targeting Pseudomonas aeruginosa. Cell, 186:5098-5113.e19, 2023 Cited by PubMed: 37918395 DOI: 10.1016/j.cell.2023.10.002 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4.6 Å)

Structure validation