8CPE
CryoEM structure of AL55 amyloid fibrils extracted from the kidney of an AL amyloidosis patient.
Summary for 8CPE
| Entry DOI | 10.2210/pdb8cpe/pdb |
| Related | 6HUD |
| EMDB information | 0274 16780 |
| Descriptor | Immunoglobulin lambda light chain (1 entity in total) |
| Functional Keywords | light chains, amyloid fibrils, al amyloidosis., protein fibril |
| Biological source | Homo sapiens |
| Total number of polymer chains | 5 |
| Total formula weight | 116632.79 |
| Authors | Puri, S.,Schulte, T.,Chaves-Sanjuan, A.,Ricagno, S. (deposition date: 2023-03-02, release date: 2023-08-16) |
| Primary citation | Puri, S.,Schulte, T.,Chaves-Sanjuan, A.,Mazzini, G.,Caminito, S.,Pappone, C.,Anastasia, L.,Milani, P.,Merlini, G.,Bolognesi, M.,Nuvolone, M.,Palladini, G.,Ricagno, S. The Cryo-EM STRUCTURE of Renal Amyloid Fibril Suggests Structurally Homogeneous Multiorgan Aggregation in AL Amyloidosis. J.Mol.Biol., 435:168215-168215, 2023 Cited by PubMed: 37516426DOI: 10.1016/j.jmb.2023.168215 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (4 Å) |
Structure validation
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