8CM9

Structure of human O-GlcNAc transferase in complex with UDP and tP11

Summary for 8CM9

Entry DOI	10.2210/pdb8cm9/pdb
Descriptor	UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, PHE-MET-PRO-LYS-TYR-SER-ILE, URIDINE-5'-DIPHOSPHATE, ... (4 entities in total)
Functional Keywords	o-glcnac, ogt, complex, transferase
Biological source	Homo sapiens (human) More
Total number of polymer chains	8
Total formula weight	329291.59
Authors	Meek, R.W.,Davies, G.J. (deposition date: 2023-02-18, release date: 2023-10-04, Last modification date: 2024-04-10)
Primary citation	Alteen, M.G.,Meek, R.W.,Kolappan, S.,Busmann, J.A.,Cao, J.,O'Gara, Z.,Chou, Y.,Derda, R.,Davies, G.J.,Vocadlo, D.J. Phage display uncovers a sequence motif that drives polypeptide binding to a conserved regulatory exosite of O-GlcNAc transferase. Proc.Natl.Acad.Sci.USA, 120:e2303690120-e2303690120, 2023 Cited by PubMed: 37819980 DOI: 10.1073/pnas.2303690120 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation