8CM9
Structure of human O-GlcNAc transferase in complex with UDP and tP11
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006493 | biological_process | protein O-linked glycosylation |
| A | 0016757 | molecular_function | glycosyltransferase activity |
| B | 0006493 | biological_process | protein O-linked glycosylation |
| B | 0016757 | molecular_function | glycosyltransferase activity |
| C | 0006493 | biological_process | protein O-linked glycosylation |
| C | 0016757 | molecular_function | glycosyltransferase activity |
| D | 0006493 | biological_process | protein O-linked glycosylation |
| D | 0016757 | molecular_function | glycosyltransferase activity |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | ACT_SITE: Proton acceptor => ECO:0000305|PubMed:21240259, ECO:0000305|PubMed:26678539 |
| Chain | Residue | Details |
| A | HIS508 | |
| B | HIS508 | |
| C | HIS508 | |
| D | HIS508 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 24 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:23103939, ECO:0007744|PDB:4GYW |
| Chain | Residue | Details |
| A | GLN849 | |
| B | HIS911 | |
| B | HIS930 | |
| B | ASP935 | |
| C | GLN849 | |
| C | LYS852 | |
| C | ALA906 | |
| C | HIS911 | |
| C | HIS930 | |
| C | ASP935 | |
| D | GLN849 | |
| A | LYS852 | |
| D | LYS852 | |
| D | ALA906 | |
| D | HIS911 | |
| D | HIS930 | |
| D | ASP935 | |
| A | ALA906 | |
| A | HIS911 | |
| A | HIS930 | |
| A | ASP935 | |
| B | GLN849 | |
| B | LYS852 | |
| B | ALA906 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphothreonine; by AMPK => ECO:0000269|PubMed:24563466, ECO:0000269|PubMed:37541260 |
| Chain | Residue | Details |
| A | THR454 | |
| B | THR454 | |
| C | THR454 | |
| D | THR454 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphotyrosine => ECO:0000250|UniProtKB:P56558 |
| Chain | Residue | Details |
| A | TYR989 | |
| B | TYR989 | |
| C | TYR989 | |
| D | TYR989 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | CARBOHYD: O-linked (GlcNAc) serine; by autocatalysis => ECO:0000269|PubMed:27713473 |
| Chain | Residue | Details |
| A | SER399 | |
| B | SER399 | |
| C | SER399 | |
| D | SER399 |
