8CLS

Drosophila melanogaster insulin receptor ectodomain in complex with DILP5

8CLS の概要

• エントリーDOI: 10.2210/pdb8cls/pdb
• EMDBエントリー: 16718
• 分子名称: Insulin-like receptor, Probable insulin-like peptide 5 A chain, Probable insulin-like peptide 5 (3 entities in total)
• 機能のキーワード: dilp5 hormone, drosophila insulin-like signalling receptor, disulfide linked ectodomain, signaling protein
• 由来する生物種: Drosophila melanogaster (fruit fly); 詳細
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 257590.38

構造登録者

Viola, C.M.,Brzozowski, A.M.,Shafi, T. (登録日: 2023-02-17, 公開日: 2023-12-20)

• 主引用文献: Viola, C.M.,Frittmann, O.,Jenkins, H.T.,Shafi, T.,De Meyts, P.,Brzozowski, A.M.; Structural conservation of insulin/IGF signalling axis at the insulin receptors level in Drosophila and humans.; Nat Commun, 14:6271-6271, 2023; PubMed: 37805602; DOI: 10.1038/s41467-023-41862-x

実験手法

ELECTRON MICROSCOPY (4 Å)