8CGE

The crystal structure of a cobalt-bound scFv reveals a Tetrameric polyHistidine motif (TetrHis)

Summary for 8CGE

Entry DOI	10.2210/pdb8cge/pdb
Descriptor	Single Chain Fv 2A2, COBALT (II) ION, SULFATE ION, ... (5 entities in total)
Functional Keywords	single chain fragment variable antibody, tetrameric polyhistidine tetrhis motif, cobalt-bound, metal binding protein
Biological source	synthetic construct
Total number of polymer chains	2
Total formula weight	66521.76
Authors	Healey, R.D.,Hoh, F.,Granier, S.,Leyrat, C. (deposition date: 2023-02-03, release date: 2023-08-09)
Primary citation	Healey, R.D.,Couillaud, L.,Hoh, F.,Mouhand, A.,Fouillen, A.,Couvineau, P.,Granier, S.,Leyrat, C. Structure, dynamics and transferability of the metal-dependent polyhistidine tetramerization motif TetrHis for single-chain Fv antibodies. Commun Chem, 6:160-160, 2023 Cited by PubMed: 37507458 DOI: 10.1038/s42004-023-00962-x PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation