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8CFH

Crystal structure of S-adenosyl-L-homocysteine hydrolase from P. aeruginosa in complex with F2X-Entry library fragment C08

Summary for 8CFH
Entry DOI10.2210/pdb8cfh/pdb
DescriptorAdenosylhomocysteinase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ADENINE, ... (8 entities in total)
Functional Keywordsfragment screening, protein-ligand complex, drug discovery, sam-dependent methylation reactions, sahase, ahcy, hydrolase
Biological sourcePseudomonas aeruginosa PAO1
Total number of polymer chains4
Total formula weight213030.60
Authors
Malecki, P.H.,Gawel, M.,Stepniewska, M.,Brzezinski, K. (deposition date: 2023-02-03, release date: 2024-02-21)
Primary citationMalecki, P.H.,Gawel, M.,Stepniewska, M.,Brzezinski, K.
Crystal structure of S-adenosyl-L-homocysteine hydrolase from P. aeruginosa in complex with fragment F2X-Entry C08
To be published,
Experimental method
X-RAY DIFFRACTION (1.6 Å)
Structure validation

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