8CFH
Crystal structure of S-adenosyl-L-homocysteine hydrolase from P. aeruginosa in complex with F2X-Entry library fragment C08
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Adenosylhomocysteinase | polymer | 472 | 51735.0 | 4 | UniProt (Q9I685) Pfam (PF05221) Pfam (PF00670) | Pseudomonas aeruginosa PAO1 | S-adenosyl-L-homocysteine hydrolase,AdoHcyase |
| 2 | E, FA, N, W (A, D, B, C) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 4 | Chemie (NAD) | |||
| 3 | F, GA, O, X (A, D, B, C) | ADENINE | non-polymer | 135.1 | 4 | Chemie (ADE) | |||
| 4 | G, IA, P, Y (A, D, B, C) | POTASSIUM ION | non-polymer | 39.1 | 4 | Chemie (K) | |||
| 5 | AA, BA, CA, DA, H... (C, A, D, B) | PHOSPHATE ION | non-polymer | 95.0 | 16 | Chemie (PO4) | |||
| 6 | EA, K, L, M, NA... (C, A, D, B) | (3S)-3-hydroxy-2-methyl-2,3-dihydro-1H-isoindol-1-one | non-polymer | 163.2 | 7 | Chemie (R8V) | |||
| 7 | HA (D) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 8 | OA, PA, QA, RA (A, B, C, D) | water | water | 18.0 | 1765 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 469 (UniProt: Q9I685)
| PDB | External Database | Details |
|---|---|---|
| Ser -2 | - | expression tag |
| Asn -1 | - | expression tag |
| Ala 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 206940.1 | |
| Non-Polymers* | Number of molecules | 36 |
| Total formula weight | 6090.5 | |
| All* | Total formula weight | 213030.6 |
