8CD0
Human heparan sulfate N-deacetylase-N-sulfotransferase 1 in complex with calcium, 3'-phosphoadenosine-5'-phosphosulfate, and nanobody nAb7 (composite map and model)
Summary for 8CD0
Entry DOI | 10.2210/pdb8cd0/pdb |
Related | 1NST 8CD0 |
EMDB information | 16564 16565 |
Descriptor | Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1, Nanobody nAb7, ADENOSINE-3'-5'-DIPHOSPHATE, ... (5 entities in total) |
Functional Keywords | deacetylase, sulfotransferase, heparan sulfate, carbohydrate, glycosaminoglycan, nanobody |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 119121.21 |
Authors | Mycroft-West, C.J.,Wu, L. (deposition date: 2023-01-29, release date: 2024-02-07, Last modification date: 2024-02-28) |
Primary citation | Mycroft-West, C.J.,Abdelkarim, S.,Duyvesteyn, H.M.E.,Gandhi, N.S.,Skidmore, M.A.,Owens, R.J.,Wu, L. Structural and mechanistic characterization of bifunctional heparan sulfate N-deacetylase-N-sulfotransferase 1. Nat Commun, 15:1326-1326, 2024 Cited by PubMed: 38351061DOI: 10.1038/s41467-024-45419-4 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.42 Å) |
Structure validation
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