8C9O

Crystal structure of SARS-CoV-2 Mpro-S144A mutant in complex with 13b-K

This is a non-PDB format compatible entry.

Summary for 8C9O

• Entry DOI: 10.2210/pdb8c9o/pdb
• Descriptor: 3C-like proteinase nsp5, ~{tert}-butyl ~{N}-[1-[(2~{S})-3-cyclopropyl-1-oxidanylidene-1-[[(2~{S},3~{R})-3-oxidanyl-4-oxidanylidene-1-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]-4-[(phenylmethyl)amino]butan-2-yl]amino]propan-2-yl]-2-oxidanylidene-pyridin-3-yl]carbamate (3 entities in total)
• Functional Keywords: mpro mutations main protease sars-cov-2, antiviral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2
• Total number of polymer chains: 2
• Total formula weight: 68810.47

Authors

Ibrahim, M.,El Kilani, H.,Hilgenfeld, R. (deposition date: 2023-01-23, release date: 2024-02-07)

• Primary citation: Ibrahim, M.,El Kilani, H.,Hilgenfeld, R.; Crystal structure of SARS-CoV-2 Mpro_S144A mutant in complex with 13b-K; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.69 Å)