8C7Z

Crystal structure of the ACVR1 (ALK2) kinase in complex with the compound M4K2308

Summary for 8C7Z

• Entry DOI: 10.2210/pdb8c7z/pdb
• Descriptor: Activin receptor type I, AMMONIUM ION, 9-piperazin-1-yl-4-(3,4,5-trimethoxyphenyl)-5,6-dihydro-[1]benzoxepino[5,4-c]pyridine, ... (6 entities in total)
• Functional Keywords: bmp signalling kinase inhibitor, signaling protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 36166.26

Authors

Cros, J.,Williams, E.P.,Sweeney, M.N.,Smil, D.,Gonzalez-Alvarez, H.,Al-awar, R.,Bullock, A.N. (deposition date: 2023-01-18, release date: 2023-02-01)

• Primary citation: Cros, J.,Williams, E.P.,Sweeney, M.N.,Smil, D.,Gonzalez-Alvarez, H.,Al-awar, R.,Bullock, A.N.; Crystal structure of the ACVR1 (ALK2) kinase in complex with the compound M4K2308; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.23 Å)