8C2D

14-3-3 in complex with Pyrin pS208

This is a non-PDB format compatible entry.

Summary for 8C2D

• Entry DOI: 10.2210/pdb8c2d/pdb
• Descriptor: 14-3-3 protein sigma, Pyrin pS208 peptide, MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: protein-peptide interaction, phosphorylation reader protein, immunology, scaffolding, intrinsic disorder motif, protein binding
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 28651.28

Authors

Lau, R.,Ottmann, C.,Hann, M. (deposition date: 2022-12-22, release date: 2023-07-26)

• Primary citation: Lau, R.,Hann, M.M.,Ottmann, C.; Crystal structure and ligandability of the 14-3-3/pyrin interface.; Biochem.Biophys.Res.Commun., 651:1-7, 2023; PubMed: 36774661; DOI: 10.1016/j.bbrc.2023.02.013

Experimental method

X-RAY DIFFRACTION (2.15 Å)