8C2D

14-3-3 in complex with Pyrin pS208

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
AAA	0000122	biological_process	negative regulation of transcription by RNA polymerase II
AAA	0001836	biological_process	release of cytochrome c from mitochondria
AAA	0003334	biological_process	keratinocyte development
AAA	0005515	molecular_function	protein binding
AAA	0005576	cellular_component	extracellular region
AAA	0005615	cellular_component	extracellular space
AAA	0005634	cellular_component	nucleus
AAA	0005737	cellular_component	cytoplasm
AAA	0005829	cellular_component	cytosol
AAA	0006469	biological_process	negative regulation of protein kinase activity
AAA	0006611	biological_process	protein export from nucleus
AAA	0007165	biological_process	signal transduction
AAA	0008104	biological_process	protein localization
AAA	0008426	molecular_function	protein kinase C inhibitor activity
AAA	0008630	biological_process	intrinsic apoptotic signaling pathway in response to DNA damage
AAA	0010482	biological_process	regulation of epidermal cell division
AAA	0010737	biological_process	protein kinase A signaling
AAA	0010839	biological_process	negative regulation of keratinocyte proliferation
AAA	0019901	molecular_function	protein kinase binding
AAA	0030216	biological_process	keratinocyte differentiation
AAA	0030307	biological_process	positive regulation of cell growth
AAA	0031424	biological_process	keratinization
AAA	0042802	molecular_function	identical protein binding
AAA	0043588	biological_process	skin development
AAA	0043616	biological_process	keratinocyte proliferation
AAA	0045296	molecular_function	cadherin binding
AAA	0045606	biological_process	positive regulation of epidermal cell differentiation
AAA	0045785	biological_process	positive regulation of cell adhesion
AAA	0045824	biological_process	negative regulation of innate immune response
AAA	0046827	biological_process	positive regulation of protein export from nucleus
AAA	0050815	molecular_function	phosphoserine residue binding
AAA	0051219	molecular_function	phosphoprotein binding
AAA	0051726	biological_process	regulation of cell cycle
AAA	0061436	biological_process	establishment of skin barrier
AAA	0070062	cellular_component	extracellular exosome
AAA	0072089	biological_process	stem cell proliferation
AAA	0140311	molecular_function	protein sequestering activity
AAA	1903077	biological_process	negative regulation of protein localization to plasma membrane
AAA	1903829	biological_process	positive regulation of protein localization
AAA	2000647	biological_process	negative regulation of stem cell proliferation

Functional Information from PROSITE/UniProt

site_id	PS00796
Number of Residues	11
Details	1433_1 14-3-3 proteins signature 1. RNLLSVAYKNV

Chain	Residue	Details
AAA	ARG41-VAL51

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	SITE: Interaction with phosphoserine on interacting protein

Chain	Residue	Details
AAA	ARG56
AAA	ARG129

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:20068231

Chain	Residue	Details
AAA	SER5

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site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163

Chain	Residue	Details
AAA	SER74

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