8BN5
Crystal structure of the ligand-binding domain (LBD) of human iGluR Delta-1 (GluD1) in complex with GABA
Summary for 8BN5
Entry DOI | 10.2210/pdb8bn5/pdb |
Descriptor | Glutamate receptor ionotropic, delta-1, CALCIUM ION, CHLORIDE ION, ... (7 entities in total) |
Functional Keywords | ion channel, ligand binding domain, glutamate receptor, gaba, membrane protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 63499.63 |
Authors | Heroven, C.,Malinauskas, T.,Aricescu, A.R. (deposition date: 2022-11-12, release date: 2023-11-22, Last modification date: 2024-01-03) |
Primary citation | Piot, L.,Heroven, C.,Bossi, S.,Zamith, J.,Malinauskas, T.,Johnson, C.,Wennagel, D.,Stroebel, D.,Charrier, C.,Aricescu, A.R.,Mony, L.,Paoletti, P. GluD1 binds GABA and controls inhibitory plasticity. Science, 382:1389-1394, 2023 Cited by PubMed: 38060673DOI: 10.1126/science.adf3406 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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