8BJK
X-ray structure of Danio rerio histone deacetylase 6 (HDAC6) CD2 in complex with an inhibitor CPD11352
Summary for 8BJK
Entry DOI | 10.2210/pdb8bjk/pdb |
Descriptor | Histone deacetylase 6, ZINC ION, POTASSIUM ION, ... (5 entities in total) |
Functional Keywords | histone deacetylase, deacetylation, inhibitor, danio rerio, hydrolase |
Biological source | Danio rerio (zebrafish) |
Total number of polymer chains | 1 |
Total formula weight | 40397.54 |
Authors | |
Primary citation | Motlova, L.,Snajdr, I.,Kutil, Z.,Andris, E.,Ptacek, J.,Novotna, A.,Novakova, Z.,Havlinova, B.,Tueckmantel, W.,Draberova, H.,Majer, P.,Schutkowski, M.,Kozikowski, A.,Rulisek, L.,Barinka, C. Comprehensive Mechanistic View of the Hydrolysis of Oxadiazole-Based Inhibitors by Histone Deacetylase 6 (HDAC6). Acs Chem.Biol., 18:1594-1610, 2023 Cited by PubMed: 37392419DOI: 10.1021/acschembio.3c00212 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.35 Å) |
Structure validation
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