8BHG
GABA-A receptor a5 heteromer - a5V2 - Bretazenil
Summary for 8BHG
Entry DOI | 10.2210/pdb8bhg/pdb |
Descriptor | Gamma-aminobutyric acid receptor subunit alpha-5, Gamma-aminobutyric acid receptor subunit gamma-2, Bretazenil, ... (7 entities in total) |
Functional Keywords | plgic gaba neurotransmission, membrane protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 5 |
Total formula weight | 210364.94 |
Authors | Miller, P.S.,Malinauskas, T.M.,Omari, K.E.,Aricescu, A.R. (deposition date: 2022-10-31, release date: 2023-11-15, Last modification date: 2023-12-27) |
Primary citation | Kasaragod, V.B.,Malinauskas, T.,Wahid, A.A.,Lengyel, J.,Knoflach, F.,Hardwick, S.W.,Jones, C.F.,Chen, W.N.,Lucas, X.,El Omari, K.,Chirgadze, D.Y.,Aricescu, A.R.,Cecere, G.,Hernandez, M.C.,Miller, P.S. The molecular basis of drug selectivity for alpha 5 subunit-containing GABA A receptors. Nat.Struct.Mol.Biol., 30:1936-1946, 2023 Cited by PubMed: 37903907DOI: 10.1038/s41594-023-01133-1 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.39 Å) |
Structure validation
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