8BCD

Human Brr2 Helicase Region in complex with C-tail deleted Jab1 and compound 50

Summary for 8BCD

• Entry DOI: 10.2210/pdb8bcd/pdb
• Related: 8BC8 8BC9 8BCA 8BCB 8BCC 8BCE 8BCF 8BCG 8BCH
• Descriptor: U5 small nuclear ribonucleoprotein 200 kDa helicase, Pre-mRNA-processing-splicing factor 8, phenylsulfonylcarbamodithioic acid (3 entities in total)
• Functional Keywords: helicase, complex, ligand, hydrolase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 230033.22

Authors

Vester, K.,Loll, B.,Wahl, M.C. (deposition date: 2022-10-15, release date: 2023-03-08, Last modification date: 2024-02-07)

• Primary citation: Vester, K.,Metz, A.,Huber, S.,Loll, B.,Wahl, M.C.; Conformation-dependent ligand hot spots in the spliceosomal RNA helicase BRR2.; Acta Crystallogr D Struct Biol, 79:304-317, 2023; PubMed: 36974964; DOI: 10.1107/S2059798323001778

Experimental method

X-RAY DIFFRACTION (3.5 Å)