8B66

Human Aldose Reductase Mutant A299G in Complex with a Ligand with an IDD Structure (3-({[2-(carboxymethoxy)-4-fluorobenzoyl]amino}methyl)benzoic acid)

Summary for 8B66

• Entry DOI: 10.2210/pdb8b66/pdb
• Descriptor: Aldo-keto reductase family 1 member B1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, CITRIC ACID, ... (5 entities in total)
• Functional Keywords: human aldose reductase, har, aldo-keto-reductase, sar_061 ligand, nadp+, diabetes, mutant a299g, closed transient pocket, oxidoreductase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 37392.37

Authors

Hubert, L.-S.,Heine, A.,Klebe, G. (deposition date: 2022-09-26, release date: 2023-10-11)

• Primary citation: Hubert, L.-S.,Heine, A.,Klebe, G.; Human Aldose Reductase Mutant A299G in Complex with a Ligand with an IDD Structure (3-({[2-(carboxymethoxy)-4-fluorobenzoyl]amino}methyl)benzoic acid); To Be Published,

Experimental method

X-RAY DIFFRACTION (0.95 Å)