8B3R
Human Aldose Reductase Mutant A299G/L300G in Complex with a Ligand with an IDD Structure ({5-fluoro-2-[(3-nitrobenzyl)carbamoyl]phenoxy}acetic acid)
Summary for 8B3R
| Entry DOI | 10.2210/pdb8b3r/pdb |
| Descriptor | Aldo-keto reductase family 1 member B1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, {5-fluoro-2-[(3-nitrobenzyl)carbamoyl]phenoxy}acetic acid, ... (5 entities in total) |
| Functional Keywords | human aldose reductase, har, aldo-keto-reductase, a299g/l300g mutant, idd_06, nadp+, diabetes, ligand in transient pocket, no flip, oxidoreductase |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 1 |
| Total formula weight | 37304.14 |
| Authors | |
| Primary citation | Hubert, L.-S.,Heine, A.,Klebe, G.,Scheer, F. Human Aldose Reductase Mutant A299G/L300G in Complex with a Ligand with an IDD Structure ({5-fluoro-2-[(3-nitrobenzyl)carbamoyl]phenoxy}acetic acid) To Be Published, |
| Experimental method | X-RAY DIFFRACTION (0.96 Å) |
Structure validation
Download full validation report
