8AV1

Crystal structure of GSK3 beta (GSK3b) in complex with CD7.

Summary for 8AV1

Entry DOI	10.2210/pdb8av1/pdb
Descriptor	Glycogen synthase kinase-3 beta, SULFATE ION, 1,2-ETHANEDIOL, ... (5 entities in total)
Functional Keywords	kinase, gsk3b, inhibitor, structural genomics, structural genomics consortium, sgc, transferase
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	84704.92
Authors	Chaikuad, A.,Mongin, F.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2022-08-26, release date: 2023-04-19, Last modification date: 2024-02-07)
Primary citation	Hasyeoui, M.,Lassagne, F.,Erb, W.,Nael, M.,Elokely, K.M.,Chaikuad, A.,Knapp, S.,Jorda, A.,Valles, S.L.,Quissac, E.,Verreault, M.,Robert, T.,Bach, S.,Samarat, A.,Mongin, F. Oxazolo[5,4-f]quinoxaline-type selective inhibitors of glycogen synthase kinase-3 alpha (GSK-3 alpha ): Development and impact on temozolomide treatment of glioblastoma cells. Bioorg.Chem., 134:106456-106456, 2023 Cited by PubMed: 36913879 DOI: 10.1016/j.bioorg.2023.106456 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.15 Å)

Structure validation