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8AV1

Crystal structure of GSK3 beta (GSK3b) in complex with CD7.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Glycogen synthase kinase-3 betapolymer36541689.82UniProt (P49841)
Pfam (PF00069)
Homo sapiens (human)GSK-3 beta,Serine/threonine-protein kinase GSK3B
2C, I
(A, B)
SULFATE IONnon-polymer96.12Chemie (SO4)
3D, E, F, G, J...
(A, B)
1,2-ETHANEDIOLnon-polymer62.17Chemie (EDO)
4H, M
(A, B)
2-pyridin-3-yl-8-thiomorpholin-4-yl-[1,3]oxazolo[5,4-f]quinoxalinenon-polymer349.42Chemie (O9L)
5N, O
(A, B)
waterwater18.0139Chemie (HOH)
Sequence modifications
A, B: 26 - 383 (UniProt: P49841)
PDBExternal DatabaseDetails
Ala 384-expression tag
His 385-expression tag
His 386-expression tag
His 387-expression tag
His 388-expression tag
His 389-expression tag
His 390-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight83379.5
Non-Polymers*Number of molecules11
Total formula weight1325.4
All*Total formula weight84704.9
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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