8AQL
High-resolution crystal structure of human SHMT2
Summary for 8AQL
Entry DOI | 10.2210/pdb8aql/pdb |
Descriptor | Serine hydroxymethyltransferase, mitochondrial, N-GLYCINE-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YL-METHANE], 1,2-ETHANEDIOL, ... (4 entities in total) |
Functional Keywords | one-carbon metabolism, tetrahydrofolate, folate cycle, mitochondria, transferase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 4 |
Total formula weight | 212588.80 |
Authors | Tran, L.H.,Ruszkowski, M. (deposition date: 2022-08-12, release date: 2022-10-05, Last modification date: 2024-01-31) |
Primary citation | Tran, L.H.,Ruszkowski, M. High-resolution crystal structure of human SHMT2 To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.23 Å) |
Structure validation
Download full validation report