8AQL
High-resolution crystal structure of human SHMT2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Serine hydroxymethyltransferase, mitochondrial | polymer | 476 | 52716.9 | 4 | UniProt (P34897) Pfam (PF00464) | Homo sapiens (human) | SHMT,Glycine hydroxymethyltransferase,Serine methylase |
| 2 | E, H, L, O (A, B, C, D) | N-GLYCINE-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YL-METHANE] | non-polymer | 306.2 | 4 | Chemie (PLG) | |||
| 3 | F, G, I, J, K... (A, B, C, D) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 8 | Chemie (EDO) | |||
| 4 | Q, R, S, T (A, B, C, D) | water | water | 18.0 | 1402 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 210867.4 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1721.4 | |
| All* | Total formula weight | 212588.8 |
