8APX

CryoEM structure of the Chikungunya virus nsP1 capping pores in covalent complex with a 7GMP cap structure

Summary for 8APX

Entry DOI	10.2210/pdb8apx/pdb
Related	6Z0U 8AOV 8AOW 8AOX
EMDB information	15578
Descriptor	Polyprotein P1234, ZINC ION, S-ADENOSYL-L-HOMOCYSTEINE (3 entities in total)
Functional Keywords	alphavirus replication complex capping pores membrane pore methyltransferase gunayltransferase viral protein, viral protein
Biological source	Chikungunya virus strain S27-African prototype
Total number of polymer chains	12
Total formula weight	641538.89
Authors	Jones, R.,Hons, M.,Reguera, J. (deposition date: 2022-08-10, release date: 2023-05-03)
Primary citation	Jones, R.,Hons, M.,Rabah, N.,Zamarreno, N.,Arranz, R.,Reguera, J. Structural basis and dynamics of Chikungunya alphavirus RNA capping by nsP1 capping pores. Proc.Natl.Acad.Sci.USA, 120:e2213934120-e2213934120, 2023 Cited by PubMed: 36913573 DOI: 10.1073/pnas.2213934120 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.2 Å)

Structure validation