8ACT

structure of the human beta-cardiac myosin folded-back off state

Summary for 8ACT

• Entry DOI: 10.2210/pdb8act/pdb
• EMDB information: 15353
• Descriptor: Myosin-7, Myosin light chain 3, Myosin regulatory light chain 2, ventricular/cardiac muscle isoform, ... (6 entities in total)
• Functional Keywords: cardiac myosin, myosin, human, folded-back off state, contractile protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 277479.21

Authors

Grinzato, A.,Kandiah, E.,Robert-Paganin, J.,Auguin, D.,Kikuti, C.,Nandwani, N.,Moussaoui, D.,Pathak, D.,Ruppel, K.M.,Spudich, J.A.,Houdusse, A. (deposition date: 2022-07-06, release date: 2023-06-07, Last modification date: 2023-08-30)

• Primary citation: Grinzato, A.,Auguin, D.,Kikuti, C.,Nandwani, N.,Moussaoui, D.,Pathak, D.,Kandiah, E.,Ruppel, K.M.,Spudich, J.A.,Houdusse, A.,Robert-Paganin, J.; Cryo-EM structure of the folded-back state of human beta-cardiac myosin.; Nat Commun, 14:3166-3166, 2023; PubMed: 37258552; DOI: 10.1038/s41467-023-38698-w

Experimental method

ELECTRON MICROSCOPY (3.6 Å)