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8ACT

structure of the human beta-cardiac myosin folded-back off state

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Myosin-7polymer904103807.12UniProt (P12883)
Pfam (PF02736)
Pfam (PF00063)
Homo sapiens (human)Myosin heavy chain 7,Myosin heavy chain slow isoform,MyHC-slow,Myosin heavy chain,cardiac muscle beta isoform,MyHC-beta
2C, D
(C, D)
Myosin light chain 3polymer15717895.42UniProt (P08590)Homo sapiens (human)Cardiac myosin light chain 1,CMLC1,Myosin light chain 1,slow-twitch muscle B/ventricular isoform,MLC1SB,Ventricular myosin alkali light chain,Ventricular myosin light chain 1,VLCl,Ventricular/slow twitch myosin alkali light chain,MLC-lV/sb
3E, F
(E, F)
Myosin regulatory light chain 2, ventricular/cardiac muscle isoformpolymer14416490.62UniProt (P10916)
Pfam (PF13499)
Homo sapiens (human)
4G, J
(A, B)
ADENOSINE-5'-DIPHOSPHATEnon-polymer427.22Chemie (ADP)
5H, K
(A, B)
PHOSPHATE IONnon-polymer95.02Chemie (PO4)
6I, L
(A, B)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight276386.3
Non-Polymers*Number of molecules6
Total formula weight1093.0
All*Total formula weight277479.2
*Water molecules are not included.

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PDB entries from 2026-01-07

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