8ACF

Structure of the argX-117 in complex with a complement C2 fragment at low pH

8ACF の概要

• エントリーDOI: 10.2210/pdb8acf/pdb
• 分子名称: Complement C2b fragment, Heavy chain of mAb ARGX-117 Fab, Nanobody specific for the kappa-light chain, ... (9 entities in total)
• 機能のキーワード: innate immune system, complement, antibody, immune system
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 83939.91

構造登録者

Olesen, H.G.,Andersen, G.R. (登録日: 2022-07-05, 公開日: 2024-01-17, 最終更新日: 2026-03-04)

• 主引用文献: Olesen, H.G.,Andersen, G.R.; Structure-function analysis of ARGX-117, a calcium- and pH-dependent clinical phase complement C2 blocking antibody; To be published,

実験手法

X-RAY DIFFRACTION (1.8 Å)