8A5W
Crystal structure of the human phosphoserine aminotransferase (PSAT) in complex with O-phosphoserine
Summary for 8A5W
Entry DOI | 10.2210/pdb8a5w/pdb |
Descriptor | Phosphoserine aminotransferase, (2S)-2-[(E)-[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylideneamino]-3-phosphonooxy-propanoic acid, (2~{S})-2-[[(~{R})-[[(5~{S})-5-azanyl-6-oxidanylidene-hexyl]amino]-[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methyl]amino]-3-phosphonooxy-propanoic acid, ... (9 entities in total) |
Functional Keywords | transferase, human, psat |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 8 |
Total formula weight | 325450.39 |
Authors | Costanzi, E.,Demitri, N.,Ullah, R.,Marchesan, F.,Peracchi, A.,Zangelmi, E.,Storici, P.,Campanini, B. (deposition date: 2022-06-16, release date: 2023-03-29, Last modification date: 2024-02-07) |
Primary citation | Marchesani, F.,Zangelmi, E.,Murtas, G.,Costanzi, E.,Ullah, R.,Peracchi, A.,Bruno, S.,Pollegioni, L.,Mozzarelli, A.,Storici, P.,Campanini, B. L-serine biosynthesis in the human central nervous system: Structure and function of phosphoserine aminotransferase. Protein Sci., 32:e4609-e4609, 2023 Cited by PubMed: 36851825DOI: 10.1002/pro.4609 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.78 Å) |
Structure validation
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