8A5W

Crystal structure of the human phosphoserine aminotransferase (PSAT) in complex with O-phosphoserine

8A5W の概要

• エントリーDOI: 10.2210/pdb8a5w/pdb
• 分子名称: Phosphoserine aminotransferase, (2S)-2-[(E)-[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylideneamino]-3-phosphonooxy-propanoic acid, (2~{S})-2-[[(~{R})-[[(5~{S})-5-azanyl-6-oxidanylidene-hexyl]amino]-[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methyl]amino]-3-phosphonooxy-propanoic acid, ... (9 entities in total)
• 機能のキーワード: transferase, human, psat
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 325450.39

構造登録者

Costanzi, E.,Demitri, N.,Ullah, R.,Marchesan, F.,Peracchi, A.,Zangelmi, E.,Storici, P.,Campanini, B. (登録日: 2022-06-16, 公開日: 2023-03-29, 最終更新日: 2024-02-07)

• 主引用文献: Marchesani, F.,Zangelmi, E.,Murtas, G.,Costanzi, E.,Ullah, R.,Peracchi, A.,Bruno, S.,Pollegioni, L.,Mozzarelli, A.,Storici, P.,Campanini, B.; L-serine biosynthesis in the human central nervous system: Structure and function of phosphoserine aminotransferase.; Protein Sci., 32:e4609-e4609, 2023; PubMed: 36851825; DOI: 10.1002/pro.4609

実験手法

X-RAY DIFFRACTION (2.78 Å)