8A49
Endoglycosidase S in complex with IgG1 Fc
Summary for 8A49
Entry DOI | 10.2210/pdb8a49/pdb |
Descriptor | IgG1 Fc, Secreted endoglycosidase EndoS, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total) |
Functional Keywords | endoglycosidase, antibody, complex, immune system |
Biological source | Homo sapiens More |
Total number of polymer chains | 4 |
Total formula weight | 257490.20 |
Authors | Sudol, A.S.L.,Tews, I.,Crispin, M. (deposition date: 2022-06-10, release date: 2022-11-30, Last modification date: 2024-01-31) |
Primary citation | Sudol, A.S.L.,Butler, J.,Ivory, D.P.,Tews, I.,Crispin, M. Extensive substrate recognition by the streptococcal antibody-degrading enzymes IdeS and EndoS. Nat Commun, 13:7801-7801, 2022 Cited by PubMed: 36528711DOI: 10.1038/s41467-022-35340-z PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.45 Å) |
Structure validation
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