8A48

Less crystallisable" IgG1 Fc fragment (E382S variant)

Summary for 8A48

• Entry DOI: 10.2210/pdb8a48/pdb
• Descriptor: IgG1 Fc, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• Functional Keywords: antibody, igg, fc, fragment crystallisable, immune system
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 53961.53

Authors

Sudol, A.S.L.,Tews, I.,Crispin, M. (deposition date: 2022-06-10, release date: 2022-11-30, Last modification date: 2024-01-31)

• Primary citation: Sudol, A.S.L.,Butler, J.,Ivory, D.P.,Tews, I.,Crispin, M.; Extensive substrate recognition by the streptococcal antibody-degrading enzymes IdeS and EndoS.; Nat Commun, 13:7801-7801, 2022; PubMed: 36528711; DOI: 10.1038/s41467-022-35340-z

Experimental method

X-RAY DIFFRACTION (3.044 Å)