8ZCJ
Cryo-EM structure of the pasireotide-bound SSTR5-Gi complex
Summary for 8ZCJ
Entry DOI | 10.2210/pdb8zcj/pdb |
EMDB information | 39931 |
Descriptor | Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total) |
Functional Keywords | pasireotide, sstr5, cryo-em, membrane protein/immune system, membrane protein-immune system complex |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 6 |
Total formula weight | 184976.49 |
Authors | Li, Y.G.,Meng, X.Y.,Yang, X.R.,Ling, S.L.,Shi, P.,Tian, C.L.,Yang, F. (deposition date: 2024-04-29, release date: 2024-07-10) |
Primary citation | Li, Y.G.,Meng, X.Y.,Yang, X.,Ling, S.L.,Shi, P.,Tian, C.L.,Yang, F. Structural insights into somatostatin receptor 5 bound with cyclic peptides. Acta Pharmacol.Sin., 2024 Cited by PubMed: 38926478DOI: 10.1038/s41401-024-01314-8 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.09 Å) |
Structure validation
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