8Z8L

structure of IL-4Ra in complex with an nanobody 4E9

Summary for 8Z8L

• Entry DOI: 10.2210/pdb8z8l/pdb
• Descriptor: Interleukin-4 receptor subunit alpha, nanobody dAb1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: inflammation, cytokine, antibody, immune disorder
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 38788.14

Authors

Song, G.,Qiu, W. (deposition date: 2024-04-22, release date: 2025-04-30, Last modification date: 2026-05-13)

• Primary citation: Qiu, W.,Meng, J.,Su, Z.,Xie, W.,Song, G.; Structural insight into interleukin-4R alpha and interleukin-5 inhibition by nanobodies from a bispecific antibody.; MedComm (2020), 5:e700-e700, 2024; PubMed: 39252822; DOI: 10.1002/mco2.700

Experimental method

X-RAY DIFFRACTION (3.96 Å)