8Z8L
structure of IL-4Ra in complex with an nanobody 4E9
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A (B) | Interleukin-4 receptor subunit alpha | polymer | 214 | 24622.5 | 1 | UniProt (P24394) Pfam (PF09238) | Homo sapiens (human) | IL-4 receptor subunit alpha,IL-4R subunit alpha,IL-4R-alpha,IL-4RA |
2 | B (A) | nanobody dAb1 | polymer | 124 | 13520.0 | 1 | Vicugna pacos | ||
3 | C (C) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
4 | D (B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) |
Sequence modifications
B: 1 - 207 (UniProt: P24394)
PDB | External Database | Details |
---|---|---|
Ala 182 | Cys 207 | engineered mutation |
His 208 | - | expression tag |
His 209 | - | expression tag |
His 210 | - | expression tag |
His 211 | - | expression tag |
His 212 | - | expression tag |
His 213 | - | expression tag |
Ala 214 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 38142.5 | |
Branched | Number of molecules | 1 |
Total formula weight | 424.4 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 221.2 | |
All* | Total formula weight | 38788.1 |