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8Z8L

structure of IL-4Ra in complex with an nanobody 4E9

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(B)
Interleukin-4 receptor subunit alphapolymer21424622.51UniProt (P24394)
Pfam (PF09238)
Homo sapiens (human)IL-4 receptor subunit alpha,IL-4R subunit alpha,IL-4R-alpha,IL-4RA
2B
(A)
nanobody dAb1polymer12413520.01Vicugna pacos
3C
(C)
2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched424.41In PDB
GlyTouCan (G42666HT)
4D
(B)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.21Chemie (NAG)
Sequence modifications
B: 1 - 207 (UniProt: P24394)
PDBExternal DatabaseDetails
Ala 182Cys 207engineered mutation
His 208-expression tag
His 209-expression tag
His 210-expression tag
His 211-expression tag
His 212-expression tag
His 213-expression tag
Ala 214-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight38142.5
BranchedNumber of molecules1
Total formula weight424.4
Non-Polymers*Number of molecules1
Total formula weight221.2
All*Total formula weight38788.1
*Water molecules are not included.

239149

PDB entries from 2025-07-23

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