8WYP
High Resolution Crystal Structure of Brd4 BD-1 in Complex with a Novel Inhibitor Precursor
Summary for 8WYP
Entry DOI | 10.2210/pdb8wyp/pdb |
Descriptor | Bromodomain-containing protein 4, 3-bromanylimidazo[1,2-a]pyridin-6-amine (3 entities in total) |
Functional Keywords | brd4 inhibitor, transcription |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 15307.28 |
Authors | |
Primary citation | Ma, X.,Wang, M.,Wang, F.,Li, J.,Zhang, Z.,Zhu, J.,Liu, B. High resolution crystal structure of BRD4-BD1 in complex with a novel inhibitor precursor. Biochem.Biophys.Res.Commun., 690:149284-149284, 2024 Cited by PubMed: 38006801DOI: 10.1016/j.bbrc.2023.149284 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.24 Å) |
Structure validation
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