8WYP
High Resolution Crystal Structure of Brd4 BD-1 in Complex with a Novel Inhibitor Precursor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Bromodomain-containing protein 4 | polymer | 125 | 14883.2 | 1 | UniProt (O60885) Pfam (PF00439) | Homo sapiens (human) | Protein HUNK1 |
| 2 | B, C (A) | 3-bromanylimidazo[1,2-a]pyridin-6-amine | non-polymer | 212.0 | 2 | Chemie (XUK) | |||
| 3 | D (A) | water | water | 18.0 | 182 | Chemie (HOH) |
Sequence modifications
A: 2 - 241 (UniProt: O60885)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 14883.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 424.1 | |
| All* | Total formula weight | 15307.3 |
