8UHB
Cryo-EM Structure of the Ro5256390-bound hTA1-Gs heterotrimer signaling complex
Summary for 8UHB
Entry DOI | 10.2210/pdb8uhb/pdb |
EMDB information | 42268 |
Descriptor | Soluble cytochrome b562,Beta-2 adrenergic receptor,Trace amine-associated receptor 1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... (6 entities in total) |
Functional Keywords | gpcr, signaling complex, trace amine-associated receptor, membrane protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 5 |
Total formula weight | 168035.26 |
Authors | Zilberg, G.,Warren, A.L.,Parpounas, A.K.,Wacker, D. (deposition date: 2023-10-08, release date: 2024-01-10, Last modification date: 2024-05-01) |
Primary citation | Zilberg, G.,Parpounas, A.K.,Warren, A.L.,Yang, S.,Wacker, D. Molecular basis of human trace amine-associated receptor 1 activation. Nat Commun, 15:108-108, 2024 Cited by PubMed: 38168118DOI: 10.1038/s41467-023-44601-4 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.35 Å) |
Structure validation
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