8UH3
Serotonin 1E receptor (5-HT1eR)-Gi1 Complex bound with Setiptiline
Summary for 8UH3
Entry DOI | 10.2210/pdb8uh3/pdb |
Related | 8UGY |
EMDB information | 42245 |
Descriptor | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, 5-hydroxytryptamine receptor 1E, ... (8 entities in total) |
Functional Keywords | complex, gpcr, signaling protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 5 |
Total formula weight | 159088.23 |
Authors | Wacker, D.,Parpounas, A.K.,Warren, A.L.,Zilberg, G. (deposition date: 2023-10-06, release date: 2024-05-01, Last modification date: 2024-05-08) |
Primary citation | Zilberg, G.,Parpounas, A.K.,Warren, A.L.,Fiorillo, B.,Provasi, D.,Filizola, M.,Wacker, D. Structural insights into the unexpected agonism of tetracyclic antidepressants at serotonin receptors 5-HT 1e R and 5-HT 1F R. Sci Adv, 10:eadk4855-eadk4855, 2024 Cited by PubMed: 38630816DOI: 10.1126/sciadv.adk4855 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.31 Å) |
Structure validation
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