8TGO
Crystal structure of the BG505 triple tandem trimer gp140 HIV-1 Env in complex with PGT124 and 35O22
This is a non-PDB format compatible entry.
Summary for 8TGO
Entry DOI | 10.2210/pdb8tgo/pdb |
Descriptor | Envelope glycoprotein gp41, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (11 entities in total) |
Functional Keywords | hiv, envelope, antibody, viral protein-immune system complex, viral protein/immune system |
Biological source | Human immunodeficiency virus 1 More |
Total number of polymer chains | 15 |
Total formula weight | 476175.39 |
Authors | |
Primary citation | Del Moral-Sanchez, I.,Wee, E.G.,Xian, Y.,Lee, W.H.,Allen, J.D.,Torrents de la Pena, A.,Froes Rocha, R.,Ferguson, J.,Leon, A.N.,Koekkoek, S.,Schermer, E.E.,Burger, J.A.,Kumar, S.,Zwolsman, R.,Brinkkemper, M.,Aartse, A.,Eggink, D.,Han, J.,Yuan, M.,Crispin, M.,Ozorowski, G.,Ward, A.B.,Wilson, I.A.,Hanke, T.,Sliepen, K.,Sanders, R.W. Triple tandem trimer immunogens for HIV-1 and influenza nucleic acid-based vaccines. Npj Vaccines, 9:74-74, 2024 Cited by PubMed: 38582771DOI: 10.1038/s41541-024-00862-8 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (5.75 Å) |
Structure validation
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