8SRF
Cryo-EM structure of TRPM2 chanzyme in the presence of Magnesium, ADP-ribose, Adenosine monophosphate, and Ribose-5-phosphate, closed state
Summary for 8SRF
Entry DOI | 10.2210/pdb8srf/pdb |
EMDB information | 40729 40870 40881 |
Descriptor | TRPM2 chanzyme, 5-O-phosphono-beta-D-ribofuranose, ADENOSINE MONOPHOSPHATE, ... (7 entities in total) |
Functional Keywords | trpm2 chanzyme, channel-enzyme, membrane protein |
Biological source | Salpingoeca rosetta |
Total number of polymer chains | 4 |
Total formula weight | 682706.78 |
Authors | |
Primary citation | Huang, Y.,Lu, W.,Du, J. Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution To Be Published, |
Experimental method | ELECTRON MICROSCOPY (2.52 Å) |
Structure validation
Download full validation report