8Q9Z
Cryo-EM structure of Cx26 gap junction K125E mutant in bicarbonate buffer (classification on hemichannel)
Summary for 8Q9Z
Entry DOI | 10.2210/pdb8q9z/pdb |
EMDB information | 18290 |
Descriptor | Gap junction beta-2 protein, DODECYL-BETA-D-MALTOSIDE, PHOSPHATIDYLETHANOLAMINE, ... (4 entities in total) |
Functional Keywords | gap junction large pore channel carbon dioxide sensitive, membrane protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 12 |
Total formula weight | 349094.44 |
Authors | Brotherton, D.H.,Cameron, A.D. (deposition date: 2023-08-22, release date: 2024-06-12, Last modification date: 2024-06-19) |
Primary citation | Brotherton, D.H.,Nijjar, S.,Savva, C.G.,Dale, N.,Cameron, A.D. Structures of wild-type and a constitutively closed mutant of connexin26 shed light on channel regulation by CO 2. Elife, 13:-, 2024 Cited by PubMed: 38829031DOI: 10.7554/eLife.93686 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.4 Å) |
Structure validation
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