8Q9Z
Cryo-EM structure of Cx26 gap junction K125E mutant in bicarbonate buffer (classification on hemichannel)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... | Gap junction beta-2 protein | polymer | 230 | 26713.6 | 12 | UniProt (P29033) Pfam (PF00029) In PDB | Homo sapiens (human) | |
| 2 | J, D, K, E, L... | DODECYL-BETA-D-MALTOSIDE | non-polymer | 510.6 | 30 | Chemie (LMT) | |||
| 3 | C, D, K, L, E... | PHOSPHATIDYLETHANOLAMINE | non-polymer | 734.0 | 18 | Chemie (PTY) | |||
| 4 | water | water | 18.0 | 348 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H, I, J, K, L: 1 - 226 (UniProt: P29033)
| PDB | External Database | Details |
|---|---|---|
| Glu 125 | Lys 125 | engineered mutation |
| Leu 227 | - | expression tag |
| Val 228 | - | expression tag |
| Pro 229 | - | expression tag |
| Arg 230 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 320563.3 | |
| Non-Polymers* | Number of molecules | 48 |
| Total formula weight | 28531.2 | |
| All* | Total formula weight | 349094.4 |
