8Q8G

Crystal structure of HsRNMT complexed with inhibitor DDD1870799

Summary for 8Q8G

• Entry DOI: 10.2210/pdb8q8g/pdb
• Related: 5E8J 8Q69
• Descriptor: mRNA cap guanine-N7 methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, 2-(4-fluorophenyl)-1-[(3~{S})-3-(6-oxidanyl-1~{H}-pyrazolo[3,4-b]pyridin-3-yl)piperidin-1-yl]ethanone, ... (6 entities in total)
• Functional Keywords: methyl transferase, rna binding protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 67051.07

Authors

Petit, A.P.,Fyfe, P.K. (deposition date: 2023-08-18, release date: 2024-08-28)

• Primary citation: Petit, A.P.,Fyfe, P.K.; Structure-Guided Design of HsRNMT inhibitors; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.4 Å)