8PTZ

Cryo-EM structure of human Elp123 in complex with tRNA, S-ethyl-CoA, 5'-deoxyadenosine and methionine

Summary for 8PTZ

Entry DOI	10.2210/pdb8ptz/pdb
EMDB information	17926
Descriptor	Elongator complex protein 1, Elongator complex protein 2, Elongator complex protein 3, ... (9 entities in total)
Functional Keywords	elongator, trna modification, acetyl-coa hydrolysis, translation
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	334409.32
Authors	Abbassi, N.,Jaciuk, M.,Lin, T.-Y.,Glatt, S. (deposition date: 2023-07-16, release date: 2024-04-17, Last modification date: 2024-05-22)
Primary citation	Abbassi, N.E.,Jaciuk, M.,Scherf, D.,Bohnert, P.,Rau, A.,Hammermeister, A.,Rawski, M.,Indyka, P.,Wazny, G.,Chramiec-Glabik, A.,Dobosz, D.,Skupien-Rabian, B.,Jankowska, U.,Rappsilber, J.,Schaffrath, R.,Lin, T.Y.,Glatt, S. Cryo-EM structures of the human Elongator complex at work. Nat Commun, 15:4094-4094, 2024 Cited by PubMed: 38750017 DOI: 10.1038/s41467-024-48251-y PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.35 Å)

Structure validation