8PTZ
Cryo-EM structure of human Elp123 in complex with tRNA, S-ethyl-CoA, 5'-deoxyadenosine and methionine
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Elongator complex protein 1 | polymer | 1332 | 150427.5 | 1 | UniProt (O95163) Pfam (PF04762) In PDB | Homo sapiens (human) | ELP1,IkappaB kinase complex-associated protein,IKK complex-associated protein,p150 |
2 | B | Elongator complex protein 2 | polymer | 826 | 92597.8 | 1 | UniProt (Q6IA86) Pfam (PF00400) In PDB | Homo sapiens (human) | ELP2,SHINC-2,STAT3-interacting protein 1,StIP1 |
3 | C | Elongator complex protein 3 | polymer | 581 | 65740.5 | 1 | UniProt (Q9H9T3) Pfam (PF04055) Pfam (PF16199) In PDB | Homo sapiens (human) | hELP3,tRNA uridine(34) acetyltransferase |
4 | X | tRNA Gln | polymer | 75 | 24047.2 | 1 | Homo sapiens | ||
5 | C | IRON/SULFUR CLUSTER | non-polymer | 351.6 | 1 | Chemie (SF4) | |||
6 | C | 5'-DEOXYADENOSINE | non-polymer | 251.2 | 1 | Chemie (5AD) | |||
7 | C | S-Ethyl-CoA | non-polymer | 795.6 | 1 | Chemie (A2U) | |||
8 | C | METHIONINE | non-polymer | 149.2 | 1 | Chemie (MET) | |||
9 | X | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) |
Sequence modifications
C: 1 - 547 (UniProt: Q9H9T3)
PDB | External Database | Details |
---|---|---|
Gly 548 | - | expression tag |
Leu 549 | - | expression tag |
Glu 550 | - | expression tag |
Gly 551 | - | expression tag |
Ser 552 | - | expression tag |
Ala 553 | - | expression tag |
Trp 554 | - | expression tag |
Ser 555 | - | expression tag |
His 556 | - | expression tag |
Pro 557 | - | expression tag |
Gln 558 | - | expression tag |
Phe 559 | - | expression tag |
Glu 560 | - | expression tag |
Lys 561 | - | expression tag |
Gly 562 | - | expression tag |
Gly 563 | - | expression tag |
Gly 564 | - | expression tag |
Ser 565 | - | expression tag |
Gly 566 | - | expression tag |
Gly 567 | - | expression tag |
Gly 568 | - | expression tag |
Ser 569 | - | expression tag |
Gly 570 | - | expression tag |
Gly 571 | - | expression tag |
Ser 572 | - | expression tag |
Ala 573 | - | expression tag |
Trp 574 | - | expression tag |
Ser 575 | - | expression tag |
His 576 | - | expression tag |
Pro 577 | - | expression tag |
Gln 578 | - | expression tag |
Phe 579 | - | expression tag |
Glu 580 | - | expression tag |
Lys 581 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 332813.0 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 1596.3 | |
All* | Total formula weight | 334409.3 |