Summary for 8PTT
Entry DOI | 10.2210/pdb8ptt/pdb |
Descriptor | ADP-sugar pyrophosphatase, 6-[(5~{R})-7-[3-chloranyl-4-(trifluoromethyl)phenyl]-2,7-diazaspiro[4.4]nonan-2-yl]-7-methyl-purine, MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | inhibitor, hydrolase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 4 |
Total formula weight | 99339.96 |
Authors | Diaz-Saez, L.,Koekemoer, L.,Feyerherm, C.,Sloman, S.,Fischer, C.,Schneider, S.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Huber, K.V.M. (deposition date: 2023-07-14, release date: 2024-07-24) |
Primary citation | Diaz-Saez, L.,Koekemoer, L.,Feyerherm, C.,Sloman, S.,Fischer, C.,Schneider, S.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Huber, K.V.M. Human NUDT5 in complex with MRK-952 To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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